The city of sin gets its biggest sinner yet. When Doctor Strange raises Las Vegas up from its destruction during SECRET EMPIRE, he inadvertently opens a big door for the embodiment of evil, MEPHISTO! The devilish villain takes the city for himself and sets his sights on the rest of the world. It's going to take heroes from all over the Marvel Universe to defeat him, but there's nothing simple about fighting the lord of Hell. Who escapes alive, who escapes undead and who doesn't escape at all? DAMNATION is going out in a blaze of glory, and you GOTTA see who gets burned!